Alfa Chemicals Ltd can offer a range of services to assist in the preclinical stage of your development from pre-formulation through to formulation development and transfer to cGMP clinical batch manufacture. We can also provide access to proprietary SMEDDS (Self MicroEmulsifying Drug Delivery System) formulation technology.

Please see below for the range of preclinical development services we can offer.

For further information on how Alfa can help with your formulation development needs please contact us or access the info request form.

Pre-formulation services

• API characterization
• API analytical method development
• Solubility studies
• Particle size analysis
• Excipient compatibility

Formulation development

Oral dosage forms

• Tablets - Immediate-release/ Sustained-release/ Controlled-release
• Capsules (Gelatin/HPMC) - Powders/ Pellets/ Liquids/ Hot melts/ Over-encapsulation
• Soft gelatin capsules
• Powders
• Liquids
• Self Emulsifying Lipid Formulations

Topical dosage forms

• Creams/ Ointments/ Gels/ Microemulsions

Rectal/ Vaginal dosage forms

• Suppositories
• Pessaries

Self Emulsifying Lipid Formulations

Through our partner, Gattefossé, we can offer the SELF Kit (Self Emulsifying Lipid Formulation Kit), a screening tool to evaluate Self Emulsifying Systems in early formulation work with poorly bioavailable compounds.

8 x 50 ml. samples of pre-prepared Self Emulsifying Lipid Formulations:

• Based on regulatory acceptable excipients
• Covering a wide range of API characteristics (log P, aqueous solubility, etc.)
• Provides a short-cut to development of a SEDDS or SMEDDS formulation for your drug