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Emulsifying Bases

Through our sister company Gattefossé (UK) Ltd we can offer the full range of Gattefossé lipid excipients for topical drug delivery.

Gattefossé’s emulsifying bases address many of the challenges formulators face in working with pharmaceutical actives in topical formulations, such as extremes of pH, insolubility, and heat sensitivity. Gattefossé emulsifying bases can be used to formulate topical dosage forms varying from sprayable fluid emulsions to thick creams. Combined with their excellent skin tolerance profiles, these emulsifying bases will help you develop safe and stable topical products.

Gattefossé emulsifiers are registered worldwide and commercial references are available from Australia, Asia to Europe and the USA.

For additional information on how to formulate using Gattefossé excipients please contact us, or see the Topical Emulsions, or Dermacare Kit Formulation Guides on this website. 

Products

Anionic O/W Emulsifier

Product Name Chemical Description More Information Add to My Enquiry
SEDFOS™ 75 Mixture of: Triceteareth-4 phosphate (and) Ethylene glycol palmitostearate EP/NF (and) Diethylene glycol palmitostearate EP/NF
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HLB Value 10
Melting Point °C 47.5
Recommended formulation techniques / Applications For emulsions containing difficult-to-formulate active drugs, alcoholic extracts or essential oils. From 8 to 20%, it forms creams with firm texture and has excellent heat stability. Suitable for development of anhydrous creams containing PEGs or Glycerine.

Non-ionic O/W emulsifiers

Product Name Chemical Description More Information Add to My Enquiry
Apifil® PEG-8 beeswax
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HLB Value 9
Melting Point °C 67.5
Recommended formulation techniques / Applications For emulsions containing high levels of oily phase. From 5 to 15%, it forms stable creams with firm texture and glossy appearance. For light creams, use levels of under 5% in association with an aqueous gellifying agent are recommended.
Emulcire™ 61 WL 2659 Cetyl alcohol (and) Ceteth-20 (and) Steareth-20
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HLB Value 10
Melting Point °C 48.5
Recommended formulation techniques / Applications For emulsions containing difficult-to-formulate active drugs, alcohol extracts or essential oils. From 10 to 20%, it forms soft and bright creams. Below 10%, it is used in association with other emulsifiers.
Gelot™ 64 Glyceryl monostearate EP/NF (and) PEG-75 palmitostearate
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HLB Value 10
Melting Point °C 59
Recommended formulation techniques / Applications For emulsions containing difficult-to-formulate active drugs, alcohol extracts or essential oils. From 7 to 20%, it forms creams with firm texture, has excellent heat stability and is compatible in systems covering wide pH ranges.
Tefose® 1500 PEG-6 stearate (and) PEG-32 stearate
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HLB Value 10
Melting Point °C 43.0
Recommended formulation techniques / Applications For lotions or emulsifier with light texture. It is polyvalent and compatible with all types of oils. From 8 to 12%, it forms light and soft creams. Below 8%, it forms fluid to very fluid lotions.
Tefose® 63 PEG-6 palmitostearate (and) Ethylene glycol palmitostearate EP/NF (and) PEG-32 palmitostearate
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HLB Value 9 to 10
Melting Point °C 48
Recommended formulation techniques / Applications For multipurpose types of O/W emulsions. From 8 to 20%, it forms elegant and stable creams with firm texture and excellent mucosal tolerance. Widely used in vaginal applications. For light creams, use levels of under 8% in association with an aqueous gellifying agent are recommended.

Non-ionic W/O Emulsifier

Product Name Chemical Description More Information Add to My Enquiry
Plurol Diisostearique® Triglycerol diisostearate EP
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HLB Value 4.5
Melting Point °C liquid
Recommended formulation techniques / Applications A PEG-free multipurpose W/O emulsifier. From 3 to 6%, it forms elegant and stable creams with firm texture. Strongly recommended for thermosensitive drugs requiring cold processing.